An astronaut rolled a D20 in space, so yes, you can play D&D in zero gravity

Astronaut Rabea Rogge demonstrated that playing Dungeons & Dragons is possible in zero gravity during a SpaceX mission. While rolling dice requires a specific technique, Rogge confirmed that roleplaying in space is feasible. The article also briefly mentions the increased player count for Kerbal Space Program following NASA's Artemis 2 mission.

• COMPANY Microsoft
• COMPANY Larian Studios
• GAME Dungeons & Dragons
• COMPANY SpaceX
• GAME Kerbal Space Program 2