Same receptor, two routes: Cambridge team maps the brain circuits behind obesity drugs
A study from the University of Cambridge has identified distinct brain circuits responsible for the weight loss effects of different obesity drugs. Researchers found that activating the GLP-1 receptor in the brainstem suppresses appetite, while blocking the GIPR receptor in the hypothalamus reduces weight through a separate mechanism. These findings could lead to the design of more effective combination obesity treatments.
- Entities
- Topic: Metabolism
- Topic: Neuroscience
- Game: Wegovy
- Game: Ozempic
- Person: Jo Lewis
- Game: MariTide
- Company: Cambridge University
- Game: Zepbound
- Topic: Obesity
- Game: Mounjaro
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