Ozempic

Same receptor, two routes: Cambridge team maps the brain circuits behind obesity drugs

A study from the University of Cambridge has identified distinct brain circuits responsible for the weight loss effects of different obesity drugs. Researchers found that activating the GLP-1 receptor in the brainstem suppresses appetite, while blocking the GIPR receptor in the hypothalamus reduces weight through a separate mechanism. These findings could lead to the design of more effective combination obesity treatments.