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The best Slay The Spire 2 characters ranked tier list

This guide ranks all playable characters in Slay the Spire 2, from The Silent to The Regent, based on consistency and overall performance. It considers beginner to intermediate player knowledge and does not factor in multiplayer or high Ascension levels. The Silent is ranked as the best character due to its exploitable 'Sly' keyword and ease of use.

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